Genomiverse

Sequence aligners use fixed-size k-mers in their algorithms, with the choice of k-mer size significantly impacting alignment quality. Our tool, Mapper, overcomes this by dynamically incorporating k-mers of various sizes and gaps (gapped x-mers).

Gut microbiomes share CRISPR systems through horizontal gene transfer to update their phage defense.

A novel algorithm for genetic variant identification that is 9x faster than existing tools, while producing fewer false positives and false negatives.

Antibiotic resistance genes (ARGs) are everywhere, but enrichment in human-associated environments is considered a requirement to be the highest risk (Rank I - red bars).

Antibiotic resistance genes are highly prevalent (red and blue dots) in almost all bacterial genomes. Specifically, ARGs in Gammaproteobacteria (red dots) are spreading by horizontal gene transfer via class 1 integrons (i.e. intI1).